"Exploitation of the new century's chemistry by developing new functionality and reactivity of organometallics" was taken as a challenge, by professor Nakamura Masaharu from 1st of January 2006. We welcome the ones who want to discover new reactions and functional molecules to change our society for the better, who want to improve their experimetal techniques and research ability, or who want to spend a meaningful and fulfilling research life with us.You are the ones who will add a new page in the history of this newborn laboratory.

Research topics

"Why new reactions?"

You have already learned many famous organic reactions and done retro-synthesis for complicated organic molecules during classes, so probably you are wondering what to do from now on.Future organic synthesis will try to create oils and combustibles in order to substitute the decreasing of resources that is continuing.We believe that developing new reactions and applying it in industrial chemistry for creating substances that are important as prime-materials is vital for our planet.

"What kinds of new reactions?"

Creating complicated structured molecules from simple and available molecules is the basis of organic synthetic chemistry. So, the formation of a carbon-carbon bond, the backbone of organic molecules, is one of the most important organic reactions.We try to develop new carbon-carbon bond-forming reactions from a viewpoint of "Utility of Chemical Resources".Nowadays the industrial processes have been generating large amounts of simple unsaturated hydrocarbon such as ethylene,acetylenes etc., or inactive alkyl halides. However, because of the lack of expected transformations,the use of these molecules for sophisticated organic synthesis has been limited.So far we have developed new synthetic reactions applying such unreactive molecules as chemical resources by using the features of various "organometallic reactives" such as organozinc,organomagnesium,organoindium,organoiron etc.For example, if you use our iron-catalyzed cross-coupling reactions of alkyl halides, you can make liquid crystal molecules in a fewer number of steps than before.We are now trying to develop novel synthetic reactions that will achieve the refined synthesis utilizing bio-renewable materials.


Group Motto: Toward the best synthesis for Better Society

We pursue the synthetic organic chemistry to contribute for achieving a better society. We make the next generation chemists (a scientist and an engineer, at the same time), who can challenge common practices to generate a new dogma for the better society.

Iron Catalyst Project (All staff members)


Seeking for synthetic organic chemistry in the future by iron catalysts: Synthesis of pharmaceuticals, agrochemicals, LC molecules, organic electronic materials and functional macromolecules. Development of controlled synthetic degradation (= synthetic resolution) of woody biomass.

Metalated amino acid/peptide Project (Takaya)


We are fascinated by mtalated amino acids and mult-metalated peptides bearing functional transition-metal complexes because of their unique catalytic and photoelectronic properties, which cannot be attained by the parent metal complexes. Our recent research focuses on development of artificial enzyeme by using ruthenium-complex-bound amino acids and peptide and their application to synthetic resolution of woody biomass.

Metal Nanocluster Project (Isozaki)


We are developing organotransformation catalysts for exploitation of renewable carbon resources, such as woody biomass. The catalysts are composed of the structurally well-defned metal clusters or metallic nanoparticles, which bear functional organic ligands on their surface to realize unprecedented activity and selectivity which are unattainable with the conventional metal complex catalysts. Currently, we focus on gold nanoclusters and iron oxide nanoparticles.

Photocatalytic Project (Iwamoto)

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To realize ideal chemical process, we are developing novel synthetic methods using ubiquitous, yet unutilized compounds due to their high stability. In particular, we focus on light-driven reaction with carbon dioxide or sodium chloride.

For people who are interested in our research

"What can you learn from this lab?"may be the most frequently asked question. Can you naturally get some abilities just by following the staff's instructions? The answer is NO.Unless you ask yourself WHY? you cannot progress and your efforts will only give you a part of the satisfaction that you could achieve by asking yourself questions about improving procedures and learning style.The research topic you will be given is coordinated by students in higher grades than you and by the staff, but the key to your success is how you plan your daily life in the lab starting from planning and examining experiments, analyzing data and discussing about the results.By doing so, you can learn about experimental procedures in organic chemistry including structural analysis by NMR or GC, design and simulation by using quantum calculation software, and other topics.Learning the basics, you will get one step closer to your dreams and we hope you will find a new reaction or substance you want to make and the way to do it.